TECHNOLOGY

ANTHRAX PUBLICATIONS

Mohamed, N., Clagett, M.L., Li, J., Jones, S.M., Pincus, S.E., D’Alia, G., Nardone, L. L., Babin, M., Spitalny, G.L., and Casey, L.S. A High Affinity Monoclonal Antibody to Anthrax Protective Antigen Passively Protects Rabbits Pre and Post Aerosolized Bacillus anthracis Spore Challenge. Infection & Immunity 73(2):795-802. 2005.

Casey, LS. Anti-toxin therapy as alternative to biodefense vaccines. (abstract) (submitted to Infocast Biodefense Vaccines and Therapeutics: The State of the Science Symposium)

Mohamed, N., Li, J., Ferreira, C.S., Little, S.F., Friedlander, A.M., Spitalny, G.L., and Casey, L. (2004) Enhancement of Anthrax Lethal Toxin Cytotoxicity: a Subset of Monoclonal Antibodies against Protective Antigen Increases Lethal toxin-Mediated Killing of Murine Macrophages. Infect. Immun. 72:3276-3283.

Casey, L.S., Mohamed, N., Li, J., Ferreira, C., D’Alia, G., Curtis, K., Porter, J., Pincus, S.E., Jones, S., Nardone, L., Clagett, M., Barnewall, R., Babin, M., Lyons, C.R., Spitalny, G.L. (2004) An Affinity-Enhanced Monoclonal Antibody to Anthrax Protective Antigen Completely Protects Mice and Rabbits from B. anthracis Spore Challenge. American Society for Microbiology Biodefense Research Meeting March 7-10, 2004, Baltimore, Maryland. #60(G), p. 35 (abs)

Casey, L.S., Mohamed, N., Li, J., Ferreira, C., D’Alia, G., Curtis, K., Wang, Q., Wang, S.L., Porter, J., Pincus, S.E., Nardone, L., Clagett M., Barnewall, R., Babin, M., Jones, S..M. (2004) Anthim™, an Affinity-Enhanced Monoclonal Antibody to Anthrax Protective Antigen, Protects Rabbits from B. anthracis Spore Challenge when Delivered Intramuscularly and Post Challenge. 2004 Scientific Conference for Chemical and Biological Defense Research (abs)