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Ryan D. Michalek, Ph.D.

Chief Operating Officer

As Chief Operating Officer, Dr. Michalek leverages scientific, clinical, and program management expertise to drive organizational growth through the alignment of projects with corporate objectives, the identification of strategic risks, and the development of partnership opportunities.


Dr. Michalek received his Ph.D. in microbiology and immunology from Wake Forest University with a focus on redox regulation of T cell activation. Subsequent postdoctoral studies at Duke University included foundational studies on the metabolic regulation of T cell differentiation, while biochemical profiling work with Metabolon resulted in publications encompassing cancer, autoimmune disease, and diabetes. Dr. Michalek’s experience also includes oversight of early and late phase clinical trials across several treatment modalities (cell and gene therapy, immunotherapy, small molecule inhibitors) with previous roles as the therapeutic area head of oncology for Pharm-Olam, co-chair of the Gene Therapy Operational Center of Excellence at PPD, and project leadership within IQVIA and Chiltern.


With over 30 peer-reviewed publications, ~5,000 citations, a previous appointment to the NIH Biomarker Consortium steering committee for Inflammation and Immunity, and awards from the Cancer Research Institute and American Association of Immunologists, Dr. Michalek is committed to identifying and advancing medical breakthroughs.

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